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TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities

Telomerase reverse transcriptase (TERT) promoter mutations occur frequently in cancer, have been associated with increased TERT expression and cell proliferation, and could potentially influence therapeutic regimens for melanoma. As the role of TERT expression in malignant melanoma and the non-canon...

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Detalles Bibliográficos
Autores principales: Kuhn, Christina Katharina, Meister, Jaroslawna, Kreft, Sophia, Stiller, Mathias, Puppel, Sven-Holger, Zaremba, Anne, Scheffler, Björn, Ullrich, Vivien, Schöneberg, Torsten, Schadendorf, Dirk, Horn, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328343/
https://www.ncbi.nlm.nih.gov/pubmed/37418389
http://dx.doi.org/10.1371/journal.pone.0281487