Cargando…

TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities

Telomerase reverse transcriptase (TERT) promoter mutations occur frequently in cancer, have been associated with increased TERT expression and cell proliferation, and could potentially influence therapeutic regimens for melanoma. As the role of TERT expression in malignant melanoma and the non-canon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuhn, Christina Katharina, Meister, Jaroslawna, Kreft, Sophia, Stiller, Mathias, Puppel, Sven-Holger, Zaremba, Anne, Scheffler, Björn, Ullrich, Vivien, Schöneberg, Torsten, Schadendorf, Dirk, Horn, Susanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328343/ https://www.ncbi.nlm.nih.gov/pubmed/37418389 http://dx.doi.org/10.1371/journal.pone.0281487

Ejemplares similares

Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell lines
por: Boeschen, Myriam, et al.
Publicado: (2022)

Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels
por: Kuhn, Christina, et al.
Publicado: (2023)

Single-strand DNA library preparation improves sequencing of formalin-fixed and paraffin-embedded (FFPE) cancer DNA
por: Stiller, Mathias, et al.
Publicado: (2016)

Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival
por: Ebrahimi, Azadeh, et al.
Publicado: (2022)

TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities
por: Koelsche, Christian, et al.
Publicado: (2014)

Thin PDMS Films Using Long Spin Times or Tert-Butyl Alcohol as a Solvent
por: Koschwanez, John H., et al.
Publicado: (2009)

Simulation tools for particle-based reaction-diffusion dynamics in continuous space
por: Schöneberg, Johannes, et al.
Publicado: (2014)

Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS
por: Kaczmarek, Isabell, et al.
Publicado: (2023)

Dynamical Organization of Syntaxin-1A at the Presynaptic Active Zone
por: Ullrich, Alexander, et al.
Publicado: (2015)

TERT Promoter Mutations Are Frequent in Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma
por: Griewank, Klaus G., et al.
Publicado: (2013)

TERT promoter mutations in ocular melanoma distinguish between conjunctival and uveal tumours
por: Griewank, K G, et al.
Publicado: (2013)

TERT promoter mutations and monoallelic activation of TERT in cancer
por: Huang, F W, et al.
Publicado: (2015)

Latrophilins and Teneurins in Invertebrates: No Love for Each Other?
por: Schöneberg, Torsten, et al.
Publicado: (2019)

Structural and Functional Evolution of the Trace Amine-Associated Receptors TAAR3, TAAR4 and TAAR5 in Primates
por: Stäubert, Claudia, et al.
Publicado: (2010)

Anatomical entity mention recognition at literature scale
por: Pyysalo, Sampo, et al.
Publicado: (2014)

(R)-N-{2-tert-Butyl-2-[(R)-tert-butylsulfonamido]ethylidene}-tert-butanesulfonamide
por: Hu, Yu, et al.
Publicado: (2008)

Adaptations Accumulated under Prolonged Resource Exhaustion Are Highly Transient
por: Avrani, Sarit, et al.
Publicado: (2020)

Argonaute Family Protein Expression in Normal Tissue and Cancer Entities
por: Völler, Daniel, et al.
Publicado: (2016)

Exhaust the exhausters: Targeting regulatory T cells in the tumor microenvironment
por: McRitchie, Bayley R., et al.
Publicado: (2022)

Elevated TERT Expression in TERT-Wildtype Adult Diffuse Gliomas: Histological Evaluation with a Novel TERT-Specific Antibody
por: Masui, Kenta, et al.
Publicado: (2018)

Understanding Carbon Nanotube Voltammetry: Distinguishing Adsorptive and Thin Layer Effects via “Single-Entity” Electrochemistry
por: Kaliyaraj Selva Kumar, Archana, et al.
Publicado: (2022)

Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site
por: Voelker, Hans-Ullrich, et al.
Publicado: (2017)

Nervous Exhaustion
Publicado: (1876)

UTMOST CLEEN: Development of Ultra-Thin Membrane Beam Windows for Electron Beam Exhaust Gas Treatment in the Maritime Industry
por: Sameed, Muhammed
Publicado: (2022)

Involvement of the V2 Vasopressin Receptor in Adaptation to Limited Water Supply
por: Böselt, Iris, et al.
Publicado: (2009)

Thin Functional Polymer Films by Electropolymerization
por: Palma-Cando, Alex, et al.
Publicado: (2019)

Effect of Age on Job Satisfaction and Emotional Exhaustion of Primary School Teachers in Greece
por: Anastasiou, Sophia, et al.
Publicado: (2020)

Revisiting the classification of adhesion GPCRs
por: Scholz, Nicole, et al.
Publicado: (2019)

The Evolutionary History of Vertebrate Adhesion GPCRs and Its Implication on Their Classification
por: Wittlake, Aline, et al.
Publicado: (2021)

Stachel-mediated activation of adhesion G protein-coupled receptors: insights from cryo-EM studies
por: Liebscher, Ines, et al.
Publicado: (2022)

TERT Promoter Mutations Increase Sense and Antisense Transcription from the TERT Promoter
por: Hafezi, François, et al.
Publicado: (2021)

Superconducting Thin Films
por: Bennett, Sophia Elizabeth
Publicado: (2015)

Re-expansion Pulmonary Edema—A Rare Entity: A Thin Line between Pulmonary and Cardiac Decompensation
por: Khanoria, Rita, et al.
Publicado: (2021)

β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity
por: Barella, Luiz F., et al.
Publicado: (2021)

How to wake a giant
por: Liebscher, Ines, et al.
Publicado: (2015)

4-tert-Butylpyridinium triiodide–4-tert-butylpyridine (1/1)
por: He, Hongshan, et al.
Publicado: (2011)

TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma
por: Xie, Hong, et al.
Publicado: (2014)

TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation
por: Vallarelli, Andrelou F., et al.
Publicado: (2016)

Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers
por: Stern, Josh Lewis, et al.
Publicado: (2015)

Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(−/−) mice
por: Zhou, Q-G, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_serfnkveg1q92tfrgahv5f9odl