Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells

In prostate cancer, loss of the tumour suppressor gene, Retinoblastoma (Rb), and consequent activation of transcription factor E2F1 typically occurs at a late-stage of tumour progression. It appears to regulate a switch to an androgen-independent form of cancer, castration-resistant prostate cancer...

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Detalles Bibliográficos
Autores principales: Sekar, Aashika, Leiblich, Aaron, Wainwright, S. Mark, Mendes, Cláudia C., Sarma, Dhruv, Hellberg, Josephine E. E. U., Gandy, Carina, Goberdhan, Deborah C. I., Hamdy, Freddie C., Wilson, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328346/
https://www.ncbi.nlm.nih.gov/pubmed/37363926
http://dx.doi.org/10.1371/journal.pgen.1010815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328346/
https://www.ncbi.nlm.nih.gov/pubmed/37363926
http://dx.doi.org/10.1371/journal.pgen.1010815

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