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Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators

Cardiac pump function arises from a series of highly orchestrated events across multiple scales. Computational electromechanics can encode these events in physics-constrained models. However, the large number of parameters in these models has made the systematic study of the link between cellular, t...

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Detalles Bibliográficos
Autores principales: Strocchi, Marina, Longobardi, Stefano, Augustin, Christoph M., Gsell, Matthias A. F., Petras, Argyrios, Rinaldi, Christopher A., Vigmond, Edward J., Plank, Gernot, Oates, Chris J., Wilkinson, Richard D., Niederer, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328347/
https://www.ncbi.nlm.nih.gov/pubmed/37363928
http://dx.doi.org/10.1371/journal.pcbi.1011257