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Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators
Cardiac pump function arises from a series of highly orchestrated events across multiple scales. Computational electromechanics can encode these events in physics-constrained models. However, the large number of parameters in these models has made the systematic study of the link between cellular, t...
Autores principales: | Strocchi, Marina, Longobardi, Stefano, Augustin, Christoph M., Gsell, Matthias A. F., Petras, Argyrios, Rinaldi, Christopher A., Vigmond, Edward J., Plank, Gernot, Oates, Chris J., Wilkinson, Richard D., Niederer, Steven A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328347/ https://www.ncbi.nlm.nih.gov/pubmed/37363928 http://dx.doi.org/10.1371/journal.pcbi.1011257 |
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