Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity

In skeletal muscle, muscle stem cells (MuSC) are the main cells responsible for regeneration upon injury. In diseased skeletal muscle, it would be therapeutically advantageous to replace defective MuSCs, or rejuvenate them with drugs to enhance their self-renewal and ensure long-term regenerative po...

Descripción completa

Detalles Bibliográficos
Autores principales: Dominici, Claudia, Villarreal, Oscar D, Dort, Junio, Heckel, Emilie, Wang, Yu Chang, Ragoussis, Ioannis, Joyal, Jean-Sebastien, Dumont, Nicolas, Richard, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328524/
https://www.ncbi.nlm.nih.gov/pubmed/37285284
http://dx.doi.org/10.7554/eLife.84570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328524/
https://www.ncbi.nlm.nih.gov/pubmed/37285284
http://dx.doi.org/10.7554/eLife.84570

Ejemplares similares