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Inhibition of type I PRMTs reforms muscle stem cell identity enhancing their therapeutic capacity
In skeletal muscle, muscle stem cells (MuSC) are the main cells responsible for regeneration upon injury. In diseased skeletal muscle, it would be therapeutically advantageous to replace defective MuSCs, or rejuvenate them with drugs to enhance their self-renewal and ensure long-term regenerative po...
Autores principales: | Dominici, Claudia, Villarreal, Oscar D, Dort, Junio, Heckel, Emilie, Wang, Yu Chang, Ragoussis, Ioannis, Joyal, Jean-Sebastien, Dumont, Nicolas, Richard, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328524/ https://www.ncbi.nlm.nih.gov/pubmed/37285284 http://dx.doi.org/10.7554/eLife.84570 |
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