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Drug-Dependent Morphological Transitions in Spherical and Worm-Like Polymeric Micelles Define Stability and Pharmacological Performance of Micellar Drugs

Significant advances in physicochemical properties of polymeric micelles enable optimization of therapeutic drug efficacy, supporting nanomedicine manufacturing and clinical translation. Yet, the effect of micelle morphology on pharmacological efficacy is not adequately addressed. This work addresse...

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Detalles Bibliográficos
Autores principales: Lim, Chaemin, Ramsey, Jacob D., Hwang, Duhyeong, Teixeira, Susana C. M., Poon, Chi-Duen, Strauss, Joshua D., Rosen, Elias P., Sokolsky-Papkov, Marina, Kabanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328739/
https://www.ncbi.nlm.nih.gov/pubmed/34841670
http://dx.doi.org/10.1002/smll.202103552