5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action

In the effort to identify and develop new HIV-1 inhibitors endowed with innovative mechanisms, we focused our attention on the possibility to target more than one viral encoded enzymatic function with a single molecule. In this respect, we have previously identified by virtual screening a new indoli...

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Detalles Bibliográficos
Autores principales: Corona, Angela, Meleddu, Rita, Delelis, Olivier, Subra, Frederic, Cottiglia, Filippo, Esposito, Francesca, Distinto, Simona, Maccioni, Elias, Tramontano, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328743/
https://www.ncbi.nlm.nih.gov/pubmed/37424782
http://dx.doi.org/10.3389/fcimb.2023.1193280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328743/
https://www.ncbi.nlm.nih.gov/pubmed/37424782
http://dx.doi.org/10.3389/fcimb.2023.1193280

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