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5-Nitro-3-(2-(4-phenylthiazol-2-yl)hydrazineylidene)indolin-2-one derivatives inhibit HIV-1 replication by a multitarget mechanism of action
In the effort to identify and develop new HIV-1 inhibitors endowed with innovative mechanisms, we focused our attention on the possibility to target more than one viral encoded enzymatic function with a single molecule. In this respect, we have previously identified by virtual screening a new indoli...
Autores principales: | Corona, Angela, Meleddu, Rita, Delelis, Olivier, Subra, Frederic, Cottiglia, Filippo, Esposito, Francesca, Distinto, Simona, Maccioni, Elias, Tramontano, Enzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328743/ https://www.ncbi.nlm.nih.gov/pubmed/37424782 http://dx.doi.org/10.3389/fcimb.2023.1193280 |
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