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A genetically supported drug repurposing pipeline for diabetes treatment using electronic health records

BACKGROUND: The identification of new uses for existing drug therapies has the potential to identify treatments for comorbid conditions that have the added benefit of glycemic control while also providing a rapid, low-cost approach to drug (re)discovery. METHODS: We developed and tested a geneticall...

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Detalles Bibliográficos
Autores principales: Shuey, Megan M., Lee, Kyung Min, Keaton, Jacob, Khankari, Nikhil K., Breeyear, Joseph H., Walker, Venexia M., Miller, Donald R., Heberer, Kent R., Reaven, Peter D., Clarke, Shoa L., Lee, Jennifer, Lynch, Julie A., Vujkovic, Marijana, Edwards, Todd L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328805/
https://www.ncbi.nlm.nih.gov/pubmed/37399599
http://dx.doi.org/10.1016/j.ebiom.2023.104674