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A genetically supported drug repurposing pipeline for diabetes treatment using electronic health records
BACKGROUND: The identification of new uses for existing drug therapies has the potential to identify treatments for comorbid conditions that have the added benefit of glycemic control while also providing a rapid, low-cost approach to drug (re)discovery. METHODS: We developed and tested a geneticall...
Autores principales: | Shuey, Megan M., Lee, Kyung Min, Keaton, Jacob, Khankari, Nikhil K., Breeyear, Joseph H., Walker, Venexia M., Miller, Donald R., Heberer, Kent R., Reaven, Peter D., Clarke, Shoa L., Lee, Jennifer, Lynch, Julie A., Vujkovic, Marijana, Edwards, Todd L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328805/ https://www.ncbi.nlm.nih.gov/pubmed/37399599 http://dx.doi.org/10.1016/j.ebiom.2023.104674 |
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