Design and preclinical evaluation of a novel apelin-based PET radiotracer targeting APJ receptor for molecular imaging of angiogenesis

APJ has been extensively described in the pathophysiology of angiogenesis and cell proliferation. The prognostic value of APJ overexpression in many diseases is now established. This study aimed to design a PET radiotracer that specifically binds to APJ. Apelin-F13A-NODAGA (AP747) was synthesized an...

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Detalles Bibliográficos
Autores principales: Louis, Béatrice, Nail, Vincent, Nachar, Oriane, Bouhlel, Ahlem, Moyon, Anaïs, Balasse, Laure, Simoncini, Stéphanie, Chabert, Adrien, Fernandez, Samantha, Brige, Pauline, Hache, Guillaume, Tintaru, Aura, Morgat, Clément, Dignat-George, Françoise, Garrigue, Philippe, Guillet, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328853/
https://www.ncbi.nlm.nih.gov/pubmed/36973482
http://dx.doi.org/10.1007/s10456-023-09875-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328853/
https://www.ncbi.nlm.nih.gov/pubmed/36973482
http://dx.doi.org/10.1007/s10456-023-09875-8

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