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Safety, Tolerability, and Pharmacokinetics of Recombinant Human Neuregulin-1 in Healthy Chinese Subjects

BACKGROUND: We investigated the safety, tolerability, and pharmacokinetics of intravenous recombinant human Neuregulin-1 (rhNRG-1), a DNA recombinant protein for the treatment of chronic heart failure, in healthy Chinese volunteers following single and multiple dose administration. METHODS AND RESUL...

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Detalles Bibliográficos
Autores principales: Xu, Junyu, Sun, Peihong, Zhao, Xia, Meng, Lei, Wang, Xiaorui, Qin, Xiaoyan, Zhou, Ying, Zhou, Mingdong, Cui, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328871/
https://www.ncbi.nlm.nih.gov/pubmed/37204676
http://dx.doi.org/10.1007/s40256-023-00585-6