Lateral membrane organization as target of an antimicrobial peptidomimetic compound

Antimicrobial resistance is one of the leading concerns in medical care. Here we study the mechanism of action of an antimicrobial cationic tripeptide, AMC-109, by combining high speed-atomic force microscopy, molecular dynamics, fluorescence assays, and lipidomic analysis. We show that AMC-109 acti...

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Detalles Bibliográficos
Autores principales: Melcrová, Adéla, Maity, Sourav, Melcr, Josef, de Kok, Niels A. W., Gabler, Mariella, van der Eyden, Jonne, Stensen, Wenche, Svendsen, John S. M., Driessen, Arnold J. M., Marrink, Siewert J., Roos, Wouter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328936/
https://www.ncbi.nlm.nih.gov/pubmed/37419980
http://dx.doi.org/10.1038/s41467-023-39726-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328936/
https://www.ncbi.nlm.nih.gov/pubmed/37419980
http://dx.doi.org/10.1038/s41467-023-39726-5

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