Synergistic, long-term effects of glutamate dehydrogenase 1 deficiency and mild stress on cognitive function and mPFC gene and miRNA expression

Glutamate abnormalities in the medial prefrontal cortex (mPFC) are associated with cognitive deficits. We previously showed that homozygous deletion of CNS glutamate dehydrogenase 1 (Glud1), a metabolic enzyme critical for glutamate metabolism, leads to schizophrenia-like behavioral abnormalities an...

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Detalles Bibliográficos
Autores principales: Asraf, Kfir, Zaidan, Hiba, Natoor, Baylasan, Gaisler-Salomon, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328942/
https://www.ncbi.nlm.nih.gov/pubmed/37419882
http://dx.doi.org/10.1038/s41398-023-02534-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328942/
https://www.ncbi.nlm.nih.gov/pubmed/37419882
http://dx.doi.org/10.1038/s41398-023-02534-y

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