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Porous microneedle patch with sustained delivery of extracellular vesicles mitigates severe spinal cord injury

The transplantation of mesenchymal stem cells-derived secretome, particularly extracellular vesicles is a promising therapy to suppress spinal cord injury-triggered neuroinflammation. However, efficient delivery of extracellular vesicles to the injured spinal cord, with minimal damage, remains a cha...

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Detalles Bibliográficos
Autores principales: Fang, Ao, Wang, Yifan, Guan, Naiyu, Zuo, Yanming, Lin, Lingmin, Guo, Binjie, Mo, Aisheng, Wu, Yile, Lin, Xurong, Cai, Wanxiong, Chen, Xiangfeng, Ye, Jingjia, Abdelrahman, Zeinab, Li, Xiaodan, Zheng, Hanyu, Wu, Zhonghan, Jin, Shuang, Xu, Kan, Huang, Yan, Gu, Xiaosong, Yu, Bin, Wang, Xuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328956/
https://www.ncbi.nlm.nih.gov/pubmed/37419902
http://dx.doi.org/10.1038/s41467-023-39745-2