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Methyl-CpG binding protein 2 expression is associated with symptom severity in patients with PTSD in a sex-dependent manner

Traumatic events may lead to post-traumatic stress disorder (PTSD), with higher prevalence in women. Adverse childhood experiences (ACE) increase PTSD risk in adulthood. Epigenetic mechanisms play important roles in PTSD pathogenesis and a mutation in the methyl-CpG binding protein 2 (MECP2) in mice...

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Detalles Bibliográficos
Autores principales: Cosentino, Livia, Witt, Stephanie H., Dukal, Helene, Zidda, Francesca, Siehl, Sebastian, Flor, Herta, De Filippis, Bianca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329035/
https://www.ncbi.nlm.nih.gov/pubmed/37419878
http://dx.doi.org/10.1038/s41398-023-02529-9