Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau

Insoluble fibrillar tau, the primary constituent of neurofibrillary tangles, has traditionally been thought to be the biologically active, toxic form of tau mediating neurodegeneration in Alzheimer’s disease. More recent studies have implicated soluble oligomeric tau species, referred to as high mol...

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Detalles Bibliográficos
Autores principales: Mate De Gerando, Anastasie, Welikovitch, Lindsay A., Khasnavis, Anita, Commins, Caitlin, Glynn, Calina, Chun, Joshua E., Perbet, Romain, Hyman, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329061/
https://www.ncbi.nlm.nih.gov/pubmed/37341831
http://dx.doi.org/10.1007/s00401-023-02600-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329061/
https://www.ncbi.nlm.nih.gov/pubmed/37341831
http://dx.doi.org/10.1007/s00401-023-02600-1

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