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Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes

Parkinson´s disease (PD) is a progressive neurodegenerative disorder characterized by both motor and non-motor symptoms. Aggravation of symptoms is mirrored by accumulation of protein aggregates mainly composed by alpha-synuclein in different brain regions, called Lewy bodies (LB). Previous studies...

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Detalles Bibliográficos
Autores principales: Cappelletti, Chiara, Henriksen, Sandra Pilar, Geut, Hanneke, Rozemuller, Annemieke J. M., van de Berg, Wilma D. J., Pihlstrøm, Lasse, Toft, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329075/
https://www.ncbi.nlm.nih.gov/pubmed/37347276
http://dx.doi.org/10.1007/s00401-023-02597-7