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Population dynamics of EMT elucidates the timing and distribution of phenotypic intra-tumoral heterogeneity

The Epithelial-to-Mesenchymal Transition (EMT) is a hallmark of cancer metastasis and morbidity. EMT is a non-binary process, and cells can be stably arrested en route to EMT in an intermediate hybrid state associated with enhanced tumor aggressiveness and worse patient outcomes. Understanding EMT p...

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Detalles Bibliográficos
Autores principales: Najafi, Annice, Jolly, Mohit K., George, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329148/
https://www.ncbi.nlm.nih.gov/pubmed/37426354
http://dx.doi.org/10.1016/j.isci.2023.106964