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Cutoff value of IC(50) for drug sensitivity in patient-derived tumor organoids in colorectal cancer

Patient-derived tumor organoids (PDTOs) have the potential to be used to predict the patient response to chemotherapy. However, the cutoff value of the half-maximal inhibition concentration (IC(50)) for PDTO drug sensitivity has not been validated with clinical cohort data. We established PDTOs and...

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Detalles Bibliográficos
Autores principales: Tang, Yuting, Wang, Ting, Hu, Yaowen, Ji, Hongli, Yan, Botao, Hu, Xiarong, Zeng, Yunli, Hao, Yifan, Xue, Weisong, Chen, Zexin, Lan, Jianqiang, Wang, Yanan, Deng, Haijun, Deng, Chuxia, Wu, Xiufeng, Yan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329174/
https://www.ncbi.nlm.nih.gov/pubmed/37426352
http://dx.doi.org/10.1016/j.isci.2023.107116