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Cutoff value of IC(50) for drug sensitivity in patient-derived tumor organoids in colorectal cancer
Patient-derived tumor organoids (PDTOs) have the potential to be used to predict the patient response to chemotherapy. However, the cutoff value of the half-maximal inhibition concentration (IC(50)) for PDTO drug sensitivity has not been validated with clinical cohort data. We established PDTOs and...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329174/ https://www.ncbi.nlm.nih.gov/pubmed/37426352 http://dx.doi.org/10.1016/j.isci.2023.107116 |