Potential of in vivo stress reporter models to reduce animal use and provide mechanistic insights in toxicity studies

Chemical risk assessment ensures protection from the toxic effects of drugs and manmade chemicals. To comply with regulatory guidance, studies in complex organisms are required, as well as mechanistic studies to establish the relevance of any toxicities observed to man. Although in vitro toxicity mo...

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Detalles Bibliográficos
Autores principales: Iñesta Vaquera, Francisco, Ferro, Febe, McMahon, Michael, Henderson, Colin J., Wolf, C. Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329194/
https://www.ncbi.nlm.nih.gov/pubmed/37427015
http://dx.doi.org/10.12688/f1000research.123077.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329194/
https://www.ncbi.nlm.nih.gov/pubmed/37427015
http://dx.doi.org/10.12688/f1000research.123077.2

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