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Potential of in vivo stress reporter models to reduce animal use and provide mechanistic insights in toxicity studies
Chemical risk assessment ensures protection from the toxic effects of drugs and manmade chemicals. To comply with regulatory guidance, studies in complex organisms are required, as well as mechanistic studies to establish the relevance of any toxicities observed to man. Although in vitro toxicity mo...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000 Research Limited
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329194/ https://www.ncbi.nlm.nih.gov/pubmed/37427015 http://dx.doi.org/10.12688/f1000research.123077.2 |