Simvastatin reduces high uric acid-induced oxidative stress and inflammatory response in vascular endothelial cells via nuclear factor E2-related factor 2 (Nrf2) signaling

OBJECTIVE(S): Increased oxidative stress and inflammatory response are risk factors for kidney and cardiovascular diseases in patients with hyperuricemia. Uric acid (UA) has been reported to cause inflammation and oxidative damage in cells by inhibiting the nuclear factor E2-related factor 2 (Nrf2)...

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Detalles Bibliográficos
Autores principales: Chen, Xuemeng, Xie, Li, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329240/
https://www.ncbi.nlm.nih.gov/pubmed/37427319
http://dx.doi.org/10.22038/IJBMS.2023.69187.15074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329240/
https://www.ncbi.nlm.nih.gov/pubmed/37427319
http://dx.doi.org/10.22038/IJBMS.2023.69187.15074

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