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Effects of multiple doses of montmorillonite, alone and in combination with activated charcoal, on the toxicokinetics of a single dose of digoxin in rats

OBJECTIVE(S): A narrow margin between the therapeutic and toxic doses of digoxin can result in an increased incidence of toxicity. Since digoxin has an enterohepatic cycle, multiple oral doses of absorbents like montmorillonite may be useful in the treatment of digoxin toxicity. MATERIALS AND METHOD...

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Detalles Bibliográficos
Autores principales: Heydarian, Fatemeh, Moshiri, Mohammad, Roohbakhsh, Ali, Akaberi, Maryam, Haghighizadeh, Atoosa, Ghadiri, Ameneh, Yeganeh Khorasani, Negar, Etemad, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329247/
https://www.ncbi.nlm.nih.gov/pubmed/37427323
http://dx.doi.org/10.22038/IJBMS.2023.66843.14661