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Ru360 Alleviates Postoperative Cognitive Dysfunction in Aged Mice by Inhibiting MCU-Mediated Mitochondrial Dysfunction

PURPOSE: Ru360, a selective inhibitor of mitochondrial calcium uptake, maintains mitochondrial calcium homeostasis. To evaluate whether mitochondrial calcium uniporter (MCU)-mediated mitochondrial function is associated with the pathological process of Postoperative cognitive dysfunction (POCD), elu...

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Detalles Bibliográficos
Autores principales: Xu, Xiaoxiao, Zhou, Bin, Liu, Jun, Ma, Qianli, Zhang, Tengyu, Wu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329430/
https://www.ncbi.nlm.nih.gov/pubmed/37424959
http://dx.doi.org/10.2147/NDT.S409568