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Generating interacting protein sequences using domain-to-domain translation

MOTIVATION: Being able to artificially design novel proteins of desired function is pivotal in many biological and biomedical applications. Generative statistical modeling has recently emerged as a new paradigm for designing amino acid sequences, including in particular models and embedding methods...

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Detalles Bibliográficos
Autores principales: Meynard-Piganeau, Barthelemy, Fabbri, Caterina, Weigt, Martin, Pagnani, Andrea, Feinauer, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329493/
https://www.ncbi.nlm.nih.gov/pubmed/37399105
http://dx.doi.org/10.1093/bioinformatics/btad401