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Generating interacting protein sequences using domain-to-domain translation
MOTIVATION: Being able to artificially design novel proteins of desired function is pivotal in many biological and biomedical applications. Generative statistical modeling has recently emerged as a new paradigm for designing amino acid sequences, including in particular models and embedding methods...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329493/ https://www.ncbi.nlm.nih.gov/pubmed/37399105 http://dx.doi.org/10.1093/bioinformatics/btad401 |