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Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p

BACKGROUND: Sepsis-induced acute lung injury is a common critical illness in intensive care units with no effective treatment is currently available. Small extracellular vesicles, secreted by mesenchymal stem cells (MSCs), derived from human-induced pluripotent stem cells (iMSC-sEV), possess strikin...

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Detalles Bibliográficos
Autores principales: Peng, Wei, Yang, Yun, Chen, Jiaquan, Xu, Zeyao, Lou, Yuanlei, Li, Qi, Zhao, Ning, Qian, Kejian, Liu, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329558/
https://www.ncbi.nlm.nih.gov/pubmed/37425491
http://dx.doi.org/10.1155/2023/8987049