Investigation of the structure-activity relationship at the N-terminal part of minigastrin analogs

BACKGROUND: Over the last years, several strategies have been reported to improve the metabolic stability of minigastrin analogs. However, currently applied compounds still reveal limited in vitro and in vivo stability. We thus performed a glycine scan at the N-terminus of DOTA-MGS5 (DOTA-d-Glu-Ala-...

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Detalles Bibliográficos
Autores principales: Holzleitner, Nadine, Günther, Thomas, Daoud-Gadieh, Amira, Lapa, Constantin, Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329608/
https://www.ncbi.nlm.nih.gov/pubmed/37421545
http://dx.doi.org/10.1186/s13550-023-01016-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329608/
https://www.ncbi.nlm.nih.gov/pubmed/37421545
http://dx.doi.org/10.1186/s13550-023-01016-y

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