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Defective efferocytosis by aged macrophages promotes STING signaling mediated inflammatory liver injury

Aged livers have shown aggravated liver ischemia and reperfusion (IR) injury. Timely efferocytosis of apoptotic cells is a key mechanism for avoiding excessive inflammation and tissue injury. Here, we investigated the alteration of efferocytosis by aged macrophages and its role in regulating macroph...

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Detalles Bibliográficos
Autores principales: Hu, Haoran, Cheng, Xuyu, Li, Fei, Guan, Zhu, Xu, Jian, Wu, Dongming, Gao, Yiyun, Zhan, Xinyu, Wang, Ping, Zhou, Haoming, Rao, Zhuqing, Cheng, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329662/
https://www.ncbi.nlm.nih.gov/pubmed/37422464
http://dx.doi.org/10.1038/s41420-023-01497-9