SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis

Sterol carrier protein 2 (SCP2) is highly expressed in human osteoarthritis (OA) cartilage, accompanied by ferroptosis hallmarks, especially the accumulation of lipid hydroperoxides (LPO). However, the role of SCP2 in chondrocyte ferroptosis remains unexplored. Here, we identify that SCP2 transports...

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Detalles Bibliográficos
Autores principales: Dai, Tianming, Xue, Xiang, Huang, Jian, Yang, Zhenyu, Xu, Pengfei, Wang, Min, Xu, Wuyan, Feng, Zhencheng, Zhu, Weicong, Xu, Yangyang, Chen, Junyan, Li, Siming, Meng, Qingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329676/
https://www.ncbi.nlm.nih.gov/pubmed/37422468
http://dx.doi.org/10.1038/s41420-023-01522-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329676/
https://www.ncbi.nlm.nih.gov/pubmed/37422468
http://dx.doi.org/10.1038/s41420-023-01522-x

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