Cargando…

SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis

Sterol carrier protein 2 (SCP2) is highly expressed in human osteoarthritis (OA) cartilage, accompanied by ferroptosis hallmarks, especially the accumulation of lipid hydroperoxides (LPO). However, the role of SCP2 in chondrocyte ferroptosis remains unexplored. Here, we identify that SCP2 transports...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dai, Tianming, Xue, Xiang, Huang, Jian, Yang, Zhenyu, Xu, Pengfei, Wang, Min, Xu, Wuyan, Feng, Zhencheng, Zhu, Weicong, Xu, Yangyang, Chen, Junyan, Li, Siming, Meng, Qingqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329676/ https://www.ncbi.nlm.nih.gov/pubmed/37422468 http://dx.doi.org/10.1038/s41420-023-01522-x

Ejemplares similares

PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis
por: Xue, Xiang, et al.
Publicado: (2023)

Pioglitazone-Loaded Cartilage-Targeted Nanomicelles (Pio@C-HA-DOs) for Osteoarthritis Treatment
por: Chen, Junyan, et al.
Publicado: (2023)

Role of STAR and SCP2/SCPx in the Transport of Cholesterol and Other Lipids
por: Galano, Melanie, et al.
Publicado: (2022)

Study on specific proteins involved in articular cartilage regeneration activity induced by decalcified bone transplantation
por: Wang, Min, et al.
Publicado: (2021)

Mitochondrial membrane anchored photosensitive nano-device for lipid hydroperoxides burst and inducing ferroptosis to surmount therapy-resistant cancer
por: Sang, Mangmang, et al.
Publicado: (2019)

PPAR-γ Activation Alleviates Osteoarthritis through Both the Nrf2/NLRP3 and PGC-1α/Δψ(m) Pathways by Inhibiting Pyroptosis
por: Feng, Zhencheng, et al.
Publicado: (2023)

Lipid hydroperoxides in nutrition, health, and diseases
por: MIYAZAWA, Teruo
Publicado: (2021)

Pathophysiological potential of lipid hydroperoxide intermembrane translocation: Cholesterol hydroperoxide translocation as a special case
por: Girotti, Albert W., et al.
Publicado: (2021)

Upregulation of osteoprotegerin inhibits tert-butyl hydroperoxide-induced apoptosis of human chondrocytes
por: Ren, Qifeng, et al.
Publicado: (2022)

e-SCP-ECG(+) Protocol: An Expansion on SCP-ECG Protocol for Health Telemonitoring—Pilot Implementation
por: Mandellos, George J., et al.
Publicado: (2010)

Lipid hydroperoxides promote sarcopenia through carbonyl stress
por: Eshima, Hiroaki, et al.
Publicado: (2023)

SCP2 variant is associated with alterations in lipid metabolism, brainstem neurodegeneration, and testicular defects
por: Galano, Melanie, et al.
Publicado: (2022)

Determination of Lipid Hydroperoxides in Marine Diatoms by the FOX2 Assay
por: Orefice, Ida, et al.
Publicado: (2015)

Investigation of Lipoproteins Oxidation Mechanisms by the Analysis of Lipid Hydroperoxide Isomers
por: Kato, Shunji, et al.
Publicado: (2021)

Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy
por: Brown, Jacob L., et al.
Publicado: (2022)

SCP sistema de control de pruebas
por: Muñoz Nieto Angel Eduardo
Publicado: (2004)

SCP sistema de control de posgrados
por: Domínguez Rodríguez, Saúl
Publicado: (2002)

Evaluation of lipid oxidation mechanisms in beverages and cosmetics via analysis of lipid hydroperoxide isomers
por: Ito, Junya, et al.
Publicado: (2019)

Chondrocyte ferroptosis contribute to the progression of osteoarthritis
por: Yao, Xudong, et al.
Publicado: (2020)

Analytical and Structural Tools of Lipid Hydroperoxides: Present State and Future Perspectives
por: Kontogianni, Vassiliki G., et al.
Publicado: (2022)

Ceruloplasmin Interferes with the Assessment of Blood Lipid Hydroperoxide Content in Small Ruminants
por: Cecchini Gualandi, Stefano, et al.
Publicado: (2023)

SHRM-CP/SHRM-SCP certification exam guide
por: Willer, Dory, et al.
Publicado: (2019)

SHRM-CP/SHRM-SCP certification practice exams
por: Kelly, William D, et al.
Publicado: (2019)

Salvianolic acid B regulates gene expression and promotes cell viability in chondrocytes
por: Yang, Xiaohong, et al.
Publicado: (2017)

Regulatory effects of miR-28 on osteogenic differentiation of human bone marrow mesenchymal stem cells
por: Wang, Min, et al.
Publicado: (2022)

Effects of Epigallocatechin Gallate on Tert-Butyl Hydroperoxide-Induced Mitochondrial Dysfunction in Rat Liver Mitochondria and Hepatocytes
por: Mezera, Vojtech, et al.
Publicado: (2016)

The Role of Mitochondria in T-2 Toxin-Induced Human Chondrocytes Apoptosis
por: Liu, Jiangtao, et al.
Publicado: (2014)

Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis
por: Xu, Jin, et al.
Publicado: (2023)

The Multifaceted Regulation of Mitochondria in Ferroptosis
por: Wu, Hao, et al.
Publicado: (2021)

Inhibition effect of pyridoxamine on lipid hydroperoxide-derived modifications to human serum albumin
por: Lee, Seon Hwa, et al.
Publicado: (2018)

Dietary triacylglycerol hydroperoxide is not absorbed, yet it induces the formation of other triacylglycerol hydroperoxides in the gastrointestinal tract
por: Takahashi, Takumi, et al.
Publicado: (2022)

Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis
por: Kong, Jinsong, et al.
Publicado: (2020)

Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
por: Guo, Zhou, et al.
Publicado: (2022)

Targeting cPLA(2) derived lipid hydroperoxides as a potential intervention for sarcopenia
por: Pharaoh, Gavin, et al.
Publicado: (2020)

Simple and Sensitive Method for the Quantitative Determination of Lipid Hydroperoxides by Liquid Chromatography/Mass Spectrometry
por: Liang, Chongsheng, et al.
Publicado: (2022)

The diversified role of mitochondria in ferroptosis in cancer
por: Liu, Yu’e, et al.
Publicado: (2023)

Giant crystals inside mitochondria of equine chondrocytes
por: Nürnberger, S., et al.
Publicado: (2016)

Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis
por: Liao, Peng, et al.
Publicado: (2017)

Transport of Calcium Ions into Mitochondria
por: Xu, Zhaolong, et al.
Publicado: (2016)

Corrigendum: Deferoxamine alleviates osteoarthritis by inhibiting chondrocyte ferroptosis and activating the Nrf2 pathway
por: Guo, Zhou, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vdj0hsvr4g6n67d22cqusqai22