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VDR alleviates endothelial cell injury in arteriovenous fistula through inhibition of P66Shc-mediated mitochondrial ROS

To investigate the effects and mechanism of Vitamin D receptor (VDR) signaling on arteriovenous fistula (AVF) endothelial cell injury. Venous tissues of AVF stenosis patients were collected and analyzed, vascular morphology, reactive oxygen species (ROS), and the expression of VDR, P66Shc, fibronect...

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Detalles Bibliográficos
Autores principales: Han, Ya-chun, Liu, Yu-ting, Zhang, Hao, Xu, Yong, Liu, Jun, Chen, Hong, Song, Na, Qin, Dong-lu, Yang, Shikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329703/
https://www.ncbi.nlm.nih.gov/pubmed/37422508
http://dx.doi.org/10.1038/s41598-023-37510-5