Cell-type-specific prediction of 3D chromatin organization enables high-throughput in silico genetic screening

Investigating how chromatin organization determines cell-type-specific gene expression remains challenging. Experimental methods for measuring three-dimensional chromatin organization, such as Hi-C, are costly and have technical limitations, restricting their broad application particularly in high-t...

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Detalles Bibliográficos
Autores principales: Tan, Jimin, Shenker-Tauris, Nina, Rodriguez-Hernaez, Javier, Wang, Eric, Sakellaropoulos, Theodore, Boccalatte, Francesco, Thandapani, Palaniraja, Skok, Jane, Aifantis, Iannis, Fenyö, David, Xia, Bo, Tsirigos, Aristotelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329734/
https://www.ncbi.nlm.nih.gov/pubmed/36624151
http://dx.doi.org/10.1038/s41587-022-01612-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329734/
https://www.ncbi.nlm.nih.gov/pubmed/36624151
http://dx.doi.org/10.1038/s41587-022-01612-8

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