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Astrocyte-derived SerpinA3N promotes neuroinflammation and epileptic seizures by activating the NF-κB signaling pathway in mice with temporal lobe epilepsy

Impaired activation and regulation of the extinction of inflammatory cells and molecules in injured neuronal tissues are key factors in the development of epilepsy. SerpinA3N is mainly associated with the acute phase response and inflammatory response. In our current study, transcriptomics analysis,...

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Detalles Bibliográficos
Autores principales: Liu, Chong, Zhao, Xue-Min, Wang, Qiao, Du, Ting-Ting, Zhang, Mo-Xuan, Wang, Hui-Zhi, Li, Ren-Peng, Liang, Kun, Gao, Yuan, Zhou, Si-Yu, Xue, Tao, Zhang, Jian-Guo, Han, Chun-Lei, Shi, Lin, Zhang, Liang-Wen, Meng, Fan-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10329806/
https://www.ncbi.nlm.nih.gov/pubmed/37422673
http://dx.doi.org/10.1186/s12974-023-02840-8