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Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder

Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and behavioral phenotypes. Microglia, the resident CNS macrophages, are implicated in ASD development and progression. Here we studied the imp...

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Detalles Bibliográficos
Autores principales: Guneykaya, Dilansu, Ugursu, Bilge, Logiacco, Francesca, Popp, Oliver, Feiks, Maria Almut, Meyer, Niklas, Wendt, Stefan, Semtner, Marcus, Cherif, Fatma, Gauthier, Christian, Madore, Charlotte, Yin, Zhuoran, Çınar, Özcan, Arslan, Taner, Gerevich, Zoltan, Mertins, Philipp, Butovsky, Oleg, Kettenmann, Helmut, Wolf, Susanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330133/
https://www.ncbi.nlm.nih.gov/pubmed/37001827
http://dx.doi.org/10.1016/j.bbi.2023.03.023