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Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder
Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and behavioral phenotypes. Microglia, the resident CNS macrophages, are implicated in ASD development and progression. Here we studied the imp...
Autores principales: | Guneykaya, Dilansu, Ugursu, Bilge, Logiacco, Francesca, Popp, Oliver, Feiks, Maria Almut, Meyer, Niklas, Wendt, Stefan, Semtner, Marcus, Cherif, Fatma, Gauthier, Christian, Madore, Charlotte, Yin, Zhuoran, Çınar, Özcan, Arslan, Taner, Gerevich, Zoltan, Mertins, Philipp, Butovsky, Oleg, Kettenmann, Helmut, Wolf, Susanne A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330133/ https://www.ncbi.nlm.nih.gov/pubmed/37001827 http://dx.doi.org/10.1016/j.bbi.2023.03.023 |
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