A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation

BACKGROUND AND PURPOSE: Chronic inflammation is pathogenic and contributes to human diseases, causing a significant threat to public health. The NLR family pyrin domain-containing protein 3 (NLRP3) is the best-characterized factor regulating inflammation. Therefore, targeting NLRP3 has the potential...

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Detalles Bibliográficos
Autores principales: Wang, Fangfang, Zhang, Meng, Yuan, Meng, Xia, Zixuan, Yang, Fengge, Zhang, Sihao, Lin, Tengyu, Luo, Lianxiang, Tang, Jinshan, Zhang, Youwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330222/
https://www.ncbi.nlm.nih.gov/pubmed/36788033
http://dx.doi.org/10.1111/bph.16058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330222/
https://www.ncbi.nlm.nih.gov/pubmed/36788033
http://dx.doi.org/10.1111/bph.16058

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