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A novel sorbicillinoid compound as a potent anti-inflammation agent through inducing NLRP3 protein degradation
BACKGROUND AND PURPOSE: Chronic inflammation is pathogenic and contributes to human diseases, causing a significant threat to public health. The NLR family pyrin domain-containing protein 3 (NLRP3) is the best-characterized factor regulating inflammation. Therefore, targeting NLRP3 has the potential...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330222/ https://www.ncbi.nlm.nih.gov/pubmed/36788033 http://dx.doi.org/10.1111/bph.16058 |