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Human metapneumovirus driven IFN-β production antagonizes macrophage transcriptional induction of IL1-β in response to bacterial pathogens

Human metapneumovirus (HMPV) is a pneumovirus that may cause severe respiratory disease in humans. HMPV infection has been found to increase susceptibility to bacterial superinfections leading to increased morbidity and mortality. The molecular mechanisms underlying HMPV-mediated increase in bacteri...

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Detalles Bibliográficos
Autores principales: Loevenich, Simon, Montaldo, Nicola P., Wickenhagen, Arthur, Sherstova, Tatyana, van Loon, Barbara, Boyartchuk, Victor, Anthonsen, Marit W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330783/
https://www.ncbi.nlm.nih.gov/pubmed/37435074
http://dx.doi.org/10.3389/fimmu.2023.1173605