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Chromogranin B (CHGB) is dimorphic and responsible for dominant anion channels delivered to cell surface via regulated secretion

Regulated secretion is conserved in all eukaryotes. In vertebrates granin family proteins function in all key steps of regulated secretion. Phase separation and amyloid-based storage of proteins and small molecules in secretory granules require ion homeostasis to maintain their steady states, and th...

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Detalles Bibliográficos
Autores principales: Yadav, Gaya P., Wang, Haiyuan, Ouwendijk, Joke, Cross, Stephen, Wang, Qiaochu, Qin, Feng, Verkade, Paul, Zhu, Michael X., Jiang, Qiu-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10330821/
https://www.ncbi.nlm.nih.gov/pubmed/37435575
http://dx.doi.org/10.3389/fnmol.2023.1205516