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Case Report: A severe case of immunosuppressant-refractory immune checkpoint inhibitor-mediated colitis rescued by tofacitinib

Immune checkpoint inhibitor therapy for cancer treatment can give rise to a variety of adverse events. Here we report a male patient with metastatic melanoma who experienced life-threatening colitis and duodenitis following treatment with ipilimumab and nivolumab. The patient did not respond to the...

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Detalles Bibliográficos
Autores principales: Sweep, Mark W. D., Tjan, Martijn J. H., Gorris, Mark A. J., Bol, Kalijn F., Westdorp, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331137/
https://www.ncbi.nlm.nih.gov/pubmed/37435072
http://dx.doi.org/10.3389/fimmu.2023.1212432