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Regulatory Measures to Improve the Safety of CAR-T-Cell Treatment

INTRODUCTION: Regulatory activities aim to facilitate the safe use of novel therapeutics such as genetically engineered chimeric antigen receptor (CAR)-T cells. Toxicities associated with CAR-T-cell therapies have led to modified safety management guidance in clinical trials and the implementation o...

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Detalles Bibliográficos
Autores principales: Berg, Philipp, Schönefeld, Sonja, Ruppert-Seipp, Gabriele, Funk, Markus B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331154/
https://www.ncbi.nlm.nih.gov/pubmed/37435000
http://dx.doi.org/10.1159/000526786