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Regulatory Measures to Improve the Safety of CAR-T-Cell Treatment
INTRODUCTION: Regulatory activities aim to facilitate the safe use of novel therapeutics such as genetically engineered chimeric antigen receptor (CAR)-T cells. Toxicities associated with CAR-T-cell therapies have led to modified safety management guidance in clinical trials and the implementation o...
Autores principales: | Berg, Philipp, Schönefeld, Sonja, Ruppert-Seipp, Gabriele, Funk, Markus B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331154/ https://www.ncbi.nlm.nih.gov/pubmed/37435000 http://dx.doi.org/10.1159/000526786 |
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