Endogenous Tryptophan-Derived Ah Receptor Ligands are Dissociated from CYP1A1/1B1-Dependent Negative-Feedback

The aryl hydrocarbon receptor (AHR) exerts major roles in xenobiotic metabolism, and in immune and barrier tissue homeostasis. How AHR activity is regulated by the availability of endogenous ligands is poorly understood. Potent AHR ligands have been shown to exhibit a negative feedback loop through...

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Detalles Bibliográficos
Autores principales: Dong, Fangcong, Annalora, Andrew J, Murray, Iain A, Tian, Yuan, Marcus, Craig B, Patterson, Andrew D, Perdew, Gary H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331327/
https://www.ncbi.nlm.nih.gov/pubmed/37434789
http://dx.doi.org/10.1177/11786469231182508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331327/
https://www.ncbi.nlm.nih.gov/pubmed/37434789
http://dx.doi.org/10.1177/11786469231182508

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