Selective modulation of activated protein C activities by a nonactive site–targeting nanobody library

Activated protein C (APC) is a pleiotropic coagulation protease with anticoagulant, anti-inflammatory, and cytoprotective activities. Selective modulation of these APC activities contributes to our understanding of the regulation of these physiological mechanisms and permits the development of thera...

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Detalles Bibliográficos
Autores principales: Sim, Derek S., Shukla, Meenal, Mallari, Cornell R., Fernández, José A., Xu, Xiao, Schneider, Doug, Bauzon, Maxine, Hermiston, Terry W., Mosnier, Laurent O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331410/
https://www.ncbi.nlm.nih.gov/pubmed/36735416
http://dx.doi.org/10.1182/bloodadvances.2022008740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331410/
https://www.ncbi.nlm.nih.gov/pubmed/36735416
http://dx.doi.org/10.1182/bloodadvances.2022008740

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