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Peroxiredoxin 3 Inhibits Cardiac Fibrosis in Mice via NOX4-P38 Signalling

OBJECTIVE: Peroxiredoxin-3 (Prx-3) is widely acknowledged as an antioxidant that protects against mitochondrial reactive oxygen species. Nonetheless, its role in cardiac fibrosis has not been elucidated. We aim to explore the role and mechanism of Prx-3 in cardiac fibrosis. MATERIALS AND METHODS: In...

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Detalles Bibliográficos
Autores principales: Xiong, Xiaoqi, Li, Jun, Chen, Zhen, Luo, Changjun, Wei, Wei, Li, Bing, Kang, Yi, Nong, Xiuhong, Ai, Fen, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331444/
https://www.ncbi.nlm.nih.gov/pubmed/37434456
http://dx.doi.org/10.22074/CELLJ.2023.557603.1082