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Small molecule allosteric modulation of the adenosine A(1) receptor
G protein-coupled receptors (GPCRs) represent the target for approximately a third of FDA-approved small molecule drugs. The adenosine A(1) receptor (A(1)R), one of four adenosine GPCR subtypes, has important (patho)physiological roles in humans. A(1)R has well-established roles in the regulation of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331460/ https://www.ncbi.nlm.nih.gov/pubmed/37435481 http://dx.doi.org/10.3389/fendo.2023.1184360 |